Thionyl Chloride → HCID 20030930、化合物

HRID 232231ノート

反応式

HRID 232231 の反応式
[C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[C:10](=[O:24])[C:11]([O:13][CH2:14][C:15]1[CH:20]=[CH:19][C:18]([N+:21]([O-:23])=[O:22])=[CH:17][CH:16]=1)=[O:12])([OH:3])=O.S(Cl)([Cl:27])=O>ClC(Cl)C>[Cl:27][C:10]1([C:11]([O:13][CH2:14][C:15]2[CH:16]=[CH:17][C:18]([N+:21]([O-:23])=[O:22])=[CH:19][CH:20]=2)=[O:12])[C:5]2[C:4](=[CH:9][CH:8]=[CH:7][CH:6]=2)[C:1](=[O:3])[O:24]1

参加物

4

反応物 2

HCID 24386Thionyl ChlorideHCID 86743267HCID 86743267、化合物

生成物 1

HCID 20030930HCID 20030930、化合物

試薬・触媒・溶媒 1

HCID 63651,1-Dichloroethane溶媒

実験手順

In 15 ml of dichloroethane was dissolved 580 mg of Compound (97), followed by addition of 0.58 ml of thionyl chloride. The mixture was heated for one hour under reflux. The solvent was evaporated off, and the residue was treated with isopropylether to give 500 mg of the subject Compound (98) as colorless crystals, m.p. 132°-134° C.

後処理

  1. temperatureThe mixture was heated for one hour
  2. temperatureunder reflux
  3. customThe solvent was evaporated off
  4. additionthe residue was treated with isopropylether

出典と根拠

ORDレコード
ord-89123cdad9c847ea8d5509cddc926a77
出典データセット
uspto-grants-1989_07
特許番号
US04851422

反応ノート

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