Hydrochloric Acid → HCID 15702746、化合物

HRID 232260

反応式

HRID 232260 の反応式
[C:1]1(=[O:8])[CH2:7][CH2:6][CH2:5][CH2:4][CH:3]=[CH:2]1.[C-:9]#[N:10].C([Al+]CC)C.Cl>C1(C)C=CC=CC=1>[O:8]=[C:1]1[CH2:7][CH2:6][CH2:5][CH2:4][CH:3]([C:9]#[N:10])[CH2:2]1

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 707232-Cyclohepten-1-oneHCID 16686413Diethyl aluminum cyanide

生成物 1

HCID 15702746HCID 15702746、化合物

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

To 100 mL of toluene add 2-cyclohepten-1-one (11.0 g, 0.1 mol) and 200 mL (1M solution in toluene, 0.2 mol) of diethylaluminum cyanide. Monitor the reaction by thin-layer chromatography. Upon completion add 1M aqueous HCl until gas evolution ceases. Extract twice with 100 mL of ether. Dry the organic phase with Na2SO4. Filter off the drying agent and evaporate the solvent in vacuo to obtain the title compound.

後処理

  1. customMonitor the reaction by thin-layer chromatography
  2. extractionExtract twice with 100 mL of ether
  3. dry with materialDry the organic phase with Na2SO4
  4. filtrationFilter off the drying agent
  5. customevaporate the solvent in vacuo

出典と根拠

ORDレコード
ord-e95315393a654245bf2d5423cbf03910
出典データセット
uspto-grants-1989_07
特許番号
US04851526

関連ノート

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