Nitric Acid → 2,6-Dichloro-3-nitrotoluene

HRID 232641

反応式

HRID 232641 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[CH3:9].[N+:10]([O-])([OH:12])=[O:11]>>[Cl:1][C:2]1[C:7]([N+:10]([O-:12])=[O:11])=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[CH3:9]

参加物

3

反応物 2

HCID 944Nitric AcidHCID 83682,6-Dichlorotoluene

生成物 1

HCID 971552,6-Dichloro-3-nitrotoluene

実験手順

To 2,6-dichlorotoluene (200 g) is added dropwise fuming nitric acid (d=1.52, 206 ml) at 25° to 30° C. After stirring for 30 minutes at room temperature, the mixture is poured into ice-water, extracted with diethyl ether, and the extract is washed with an aqueous sodium hydrogen carbonate solution and then dried. The solvent is distilled off under reduced pressure to give 2,6-dichloro-3-nitrotoluene as yellow crystals (253.2 g).

後処理

  1. extractionextracted with diethyl ether
  2. washthe extract is washed with an aqueous sodium hydrogen carbonate solution
  3. customdried
  4. distillationThe solvent is distilled off under reduced pressure

出典と根拠

ORDレコード
ord-ce6e3c6086de4446ad76aa28c6e59e4f
出典データセット
uspto-grants-1997_01
特許番号
US05591744

関連ノート

読み込み中…