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3-Mercaptopropionic Acid → 11-(2-Carboxyethylthio)-2-(7-chloro-6-fluoroquinolin-2-yl)methoxy-8-(2-acetylethyl)-6,11-dihydrodibenz[b,e]oxepine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Mercaptopropionic Acid | HCID 6514 | — |
| 反応物 | 2-(7-Chloro-6-fluoroquinolin-2-yl)methoxy-11-hydroxy-8-(2-acetylethyl)-6,11-dihydrodibenz[b,e]oxepine | HCID 23359136 | — |
| 生成物 | 11-(2-Carboxyethylthio)-2-(7-chloro-6-fluoroquinolin-2-yl)methoxy-8-(2-acetylethyl)-6,11-dihydrodibenz[b,e]oxepine | HCID 23359164 | — |
反応手順
2-(7-Chloro-6-fluoroquinolin-2-yl)methoxy-11-hydroxy-8-(2-acetylethyl)-6,11-dihydrodibenz[b,e]oxepine and 3-mercaptopropionic acid were used and reacted in the same manner as in Example 1 to obtain the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05591752 |
| 出典データセット | uspto-grants-1997_01 |
| ORD ID | ord-6cbb01c235ec40dea3e2acc8f6d6dbff |
| 出典メモ | uspto-grants-1997_01 |