Dimethyl Sulfoxide → 1-(4-bromo-2,5-difluoro-phenyl)-piperidin-4-one O-[1-(5-ethyl-pyrimidin-2-yl)-piperidin-4-yl]-oxime

反応式

[CH3:43][S:44]([CH3:45])=[O:46].[CH3:47][CH2:48][O:49][C:50]([CH3:51])=[O:52].[CH:33]([N:34]([CH:35]([CH3:36])[CH3:37])[CH2:38][CH3:39])([CH3:40])[CH3:41].[Cl:24][c:25]1[n:26][cH:27][c:28]([CH2:31][CH3:32])[cH:29][n:30]1.[NH:1]1[CH2:2][CH2:3][CH:4]([O:7][N:8]=[C:9]2[CH2:10][CH2:11][N:12]([c:15]3[c:16]([F:23])[cH:17][c:18]([Br:22])[c:19]([F:21])[cH:20]3)[CH2:13][CH2:14]2)[CH2:5][CH2:6]1.[OH2:42]>>[N:1]1([c:25]2[n:26][cH:27][c:28]([CH2:31][CH3:32])[cH:29][n:30]2)[CH2:2][CH2:3][CH:4]([O:7][N:8]=[C:9]2[CH2:10][CH2:11][N:12]([c:15]3[c:16]([F:23])[cH:17][c:18]([Br:22])[c:19]([F:21])[cH:20]3)[CH2:13][CH2:14]2)[CH2:5][CH2:6]1