化工社化工社 化学情報印刷レポート · 研究参考用
4-Isopropylphenylboronic acid → N-[5-(4-isopropylphenyl)thiophene-2-sulfonyl]pyrrole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Isopropylphenylboronic acid | HCID 2773480 | — |
| 反応物 | N-(5-bromothiophenesulfonyl)pyrrole | HCID 23445587 | — |
| 生成物 | N-[5-(4-isopropylphenyl)thiophene-2-sulfonyl]pyrrole | HCID 22998466 | 84% |
反応手順
N-[5-(4-isopropylphenyl)thiophene-2-sulfonyl]pyrrole was prepared in the same manner as described in Example 33C, from 4-isopropylphenyl boronic acid and N-(5-bromothiophene sulfonyl)-pyrrole. Purification by column chromatography using 10% ethyl acetate/hexanes gave the pure sulfonamide as an off white colored solid in 84% yield, m.p. 112°-114° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05594021 |
| 出典データセット | uspto-grants-1997_01 |
| ORD ID | ord-751e1ce0333f4b6d9945f5e2e9fcd00e |
| 出典メモ | uspto-grants-1997_01 |