1,3-Bis(4-fluorophenyl)prop-2-en-1-one → 1,3-Bis(4-fluorophenyl)propan-1-one
反応式
[F:1][C:2]1[CH:18]=[CH:17][C:5]([CH:6]=[CH:7][C:8]([C:10]2[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=2)=[O:9])=[CH:4][CH:3]=1>O1CCCC1.[Ni]>[F:1][C:2]1[CH:18]=[CH:17][C:5]([CH2:6][CH2:7][C:8]([C:10]2[CH:11]=[CH:12][C:13]([F:16])=[CH:14][CH:15]=2)=[O:9])=[CH:4][CH:3]=1参加物
4
実験手順
A solution of 59.9 g of 4,4'-difluorobenzylideneacetophenone in 600 ml of tetrahydrofuran is hydrogenated in the presence of 6 g of Raney nickel. After removal of the catalyst, the reaction mixture is concentrated by rotary evaporation, affording the title compound of the formula ##STR8## as a crude product with a refractive index of n20D =1.5478.
後処理
- customAfter removal of the catalyst
- concentrationthe reaction mixture is concentrated by rotary evaporation
出典と根拠
- ORDレコード
- ord-5e902176a6434dc5872890f0acd6852a
- 出典データセット
- uspto-grants-1989_10
- 特許番号
- US04874778
反応ノート
読み込み中…