Thionyl Chloride → HCID 10543482、化合物

HRID 235202ノート

反応式

HRID 235202 の反応式
O[CH:2]([C:10]1[CH:15]=[CH:14][C:13]([CH2:16][CH2:17][CH2:18][C:19]([O:21][CH3:22])=[O:20])=[CH:12][CH:11]=1)[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.S(Cl)([Cl:25])=O>C1C=CC=CC=1>[Cl:25][CH:2]([C:10]1[CH:15]=[CH:14][C:13]([CH2:16][CH2:17][CH2:18][C:19]([O:21][CH3:22])=[O:20])=[CH:12][CH:11]=1)[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

参加物

4

反応物 2

HCID 24386Thionyl ChlorideHCID 10756510HCID 10756510、化合物

生成物 1

HCID 10543482HCID 10543482、化合物

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

To a solution of 3.49 g of methyl 4-[4-(1-hydroxy-2-Phenylethyl)phenyl]butyrate in 17 ml of benzene, 1.10 ml of thionyl chloride was added dropwise under ice-cooling, and then stirring was continued at room temperature for 1.5 hours. The reaction solvent was removed under reduced pressure, and the residue was dissolved in ether. The ether layer was washed with water and dried, and then the solvent was removed under reduced pressure to yield 3.30 g of pale yellow oil.

後処理

  1. temperaturecooling
  2. customThe reaction solvent was removed under reduced pressure
  3. dissolutionthe residue was dissolved in ether
  4. washThe ether layer was washed with water
  5. customdried
  6. customthe solvent was removed under reduced pressure

出典と根拠

ORDレコード
ord-a1981cf088524d3e906f77ee928e6c61
出典データセット
uspto-grants-1997_01
特許番号
US05597848

反応ノート

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