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Hydrochloric Acid → 4-(9-Decen-1-yloxy)benzoic acid

HRID 2352588
ノート
印刷プレビュー

反応式

HRID 2352588 の反応式
Cl[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH:10]=[CH2:11].[I-].[Na+].[OH-:14].[K+].Cl.[CH3:17][C:18](=[O:21])[CH2:19][CH3:20]>>[CH2:2]([O:21][C:18]1[CH:17]=[CH:20][C:19]([C:18]([OH:21])=[O:14])=[CH:20][CH:19]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH:10]=[CH2:11]
参加物反応条件実験手順後処理出典と根拠反応ノート

参加物

6

反応物 5

HCID 313Hydrochloric AcidHCID 5238Sodium IodideHCID 6569Methyl Ethyl KetoneHCID 14797Potassium Hydroxide2 回HCID 1174513910-Chloro-1-decene

生成物 1

HCID 148765254-(9-Decen-1-yloxy)benzoic acid収率 60%

反応条件

温度
80 °C

実験手順

10.0 g of 10-chloro-1-decene obtained in Example 1.(2) was iodized by reacting it with 25 g of sodium iodide in 2-butanone for 10 hours at 80° C. The resulting reaction mixture was then washed with water and dried, and the solvent was then removed. To the obtained iodide product were added 11.5 g of ethyl p-hydroxybenzoate and 9.6 g of potassium carbonate, and the mixture was refluxed in absolute ethanol for 15 hours. To the resulting reaction mixture was then added an aqueous potassium hydroxide solution containing 4.0 g of potassium hydroxide, and the mixture was further heated at 80° C. for 5 hours. After the reaction, the resulting reaction solution was made acid with hydrochloric acid and concentrated under reduced pressure. The resulting residue was suspended in water, and the insoluble material was corrected and dried to obtain 9.5 g of p-(9-decenyloxy)benozic acid. (Yield: 60%).

後処理

  1. customfor 10 hours
  2. customat 80° C
  3. customThe resulting reaction mixture
  4. washwas then washed with water
  5. customdried
  6. customthe solvent was then removed
  7. additionTo the obtained iodide product were added 11.5 g of ethyl p-hydroxybenzoate and 9.6 g of potassium carbonate
  8. temperaturethe mixture was refluxed in absolute ethanol for 15 hours
  9. customTo the resulting reaction mixture
  10. customAfter the reaction
  11. customthe resulting reaction solution
  12. concentrationconcentrated under reduced pressure
  13. customdried
  14. customto obtain 9.5 g of p-(9-decenyloxy)benozic acid

出典と根拠

ORDレコード
ord-2cb7a94099da4bf5a212bb21e1295f7d
出典データセット
uspto-grants-1989_10
DOI
10.6084/m9.figshare.5104873.v1
特許番号
US04877858

反応ノート

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このページの内容参加物反応条件実験手順後処理出典と根拠反応ノート