2-(2-Hydroxyethyl)pyridine → 2-(Pyridin-2-yl)ethyl methanesulfonate
反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][CH2:8][OH:9].C(N(CC)CC)C.[CH3:17][S:18](Cl)(=[O:20])=[O:19]>C1COCC1>[CH3:17][S:18]([O:9][CH2:8][CH2:7][C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=1)(=[O:20])=[O:19]参加物
5
実験手順
A solution of 2-pyridin-2-yl-ethanol (Aldrich, 0.11 mL, 0.99 mmol), triethylamine (0.42 mL, 3.0 mmol), and methanesulfonyl chloride (0.12 mL, 1.5 mmol) in 5 mL THF were processed as described in Example 1C to give the crude title compound which was used directly in the next reaction.
出典と根拠
- ORDレコード
- ord-757f2626ae444f4cb2a0a50396390df1
- 出典データセット
- uspto-grants-2010_07
- 特許番号
- US07750039B2
反応ノート
読み込み中…