Methanol → N-(2-Amino-3-carboxyphenyl)-N'-(4-methyl-3-thienyl)thiourea
反応式
[C:1]([C:4]1[C:5]([NH2:11])=[C:6]([NH2:10])[CH:7]=[CH:8][CH:9]=1)([OH:3])=[O:2].[CH3:12][C:13]1[C:14]([N:18]=[C:19]=[S:20])=[CH:15][S:16][CH:17]=1.C(Cl)Cl.CO>C1COCC1>[NH2:11][C:5]1[C:4]([C:1]([OH:3])=[O:2])=[CH:9][CH:8]=[CH:7][C:6]=1[NH:10][C:19]([NH:18][C:14]1[C:13]([CH3:12])=[CH:17][S:16][CH:15]=1)=[S:20]参加物
6
実験手順
is obtained analogously to the procedure described in example 25 a) from 3-carboxy-1,2-diaminobenzene and 4-methyl-3-thienyl isothiocyanate in anhydrous THF, followed by medium-pressure chromatography on silica gel using a mixture of 12 parts of methylene chloride and 1 part of methanol. Amorphous product.
後処理
- customis obtained analogously to the procedure
出典と根拠
- ORDレコード
- ord-698d9dc2ff7a4c328cd1b848177eccca
- 出典データセット
- uspto-grants-2010_07
- 特許番号
- US07763643B2
反応ノート
読み込み中…