Sodium Carbonate → 4-methoxy-3-methylbenzonitrile

HRID 235950

反応式

HRID 235950 の反応式
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([CH:7]=[N:8]O)=[CH:5][C:4]=1[CH3:12].C([O-])([O-])=O.[Na+].[Na+]>C(OC(=O)C)(=O)C>[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]#[N:8])=[CH:5][C:4]=1[CH3:12]

参加物

4

反応物 2

HCID 10340Sodium CarbonateHCID 42375924-Methoxy-3-methylbenzaldoxime

生成物 1

HCID 136216134-methoxy-3-methylbenzonitrile

試薬・触媒・溶媒 1

HCID 7918Acetic Anhydride溶媒

実験手順

A solution of 20 (30.9 g, 0.187 mole) in of acetic anhydride (200 ml) heated at reflux for 1.5 hours, cooled to room temperature and poured with vigorous stirring into 2N aqueous Na2CO3 (2 L). Overnight refrigeration gave a solid which was collected, washed with water, and dried to give 25.6 grams (93%) of 21 m.p. 48°-50°.

後処理

  1. temperatureat reflux for 1.5 hours
  2. additionpoured
  3. customOvernight refrigeration gave a solid which
  4. customwas collected
  5. washwashed with water
  6. customdried
  7. customto give 25.6 grams (93%) of 21 m
  8. custom48°-50°

出典と根拠

ORDレコード
ord-1f39a2408f034349a2819aa25e755bed
出典データセット
uspto-grants-1987_02
特許番号
US04642311

関連ノート

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