4-(2-(4-Methyl-3-nitrophenoxy)ethyl)morpholine → 2-Methyl-5-[2-(morpholin-4-yl)ethoxy]aniline

HRID 2360276ノート

反応式

HRID 2360276 の反応式
[CH3:1][C:2]1[CH:16]=[CH:15][C:5]([O:6][CH2:7][CH2:8][N:9]2[CH2:14][CH2:13][O:12][CH2:11][CH2:10]2)=[CH:4][C:3]=1[N+:17]([O-])=O>CO.[Pd]>[CH3:1][C:2]1[CH:16]=[CH:15][C:5]([O:6][CH2:7][CH2:8][N:9]2[CH2:14][CH2:13][O:12][CH2:11][CH2:10]2)=[CH:4][C:3]=1[NH2:17]

参加物

4

反応物 1

HCID 589298674-(2-(4-Methyl-3-nitrophenoxy)ethyl)morpholine

生成物 1

HCID 393350392-Methyl-5-[2-(morpholin-4-yl)ethoxy]aniline

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

To the mixture of 4-(2-(4-methyl-3-nitrophenoxy)ethyl)morpholine (532 mg, 2 mmol) in MeOH (50 mL) was added 10% Pd/C (250 mg). The mixture was stirred under an atmosphere of H2 (balloon) overnight. The contents of the reaction mixture were then filtered and concentrated in vacuo to give the title product, which was used without further purification.

後処理

  1. filtrationThe contents of the reaction mixture were then filtered
  2. concentrationconcentrated in vacuo

出典と根拠

ORDレコード
ord-385118c164254ec5886257b7e6f813e1
出典データセット
uspto-grants-2014_04
特許番号
US08686011B2

反応ノート

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