1,2-Ethanediamine, N1,N1-bis(1-methylethyl)- → N-[2-[bis(1-Methylethyl)amino]ethyl]-3-(phenylsulfonyl)-1-piperidinecarboxamide

HRID 236114

反応式

HRID 236114 の反応式
[CH:1]([N:4]([CH2:8][CH2:9][NH2:10])[CH:5]([CH3:7])[CH3:6])([CH3:3])[CH3:2].[C:11](N1C=CN=C1)(N1C=CN=C1)=[O:12].[C:23]1([S:29]([CH:32]2[CH2:37][CH2:36][CH2:35][NH:34][CH2:33]2)(=[O:31])=[O:30])[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[CH3:2][CH:1]([N:4]([CH:5]([CH3:7])[CH3:6])[CH2:8][CH2:9][NH:10][C:11]([N:34]1[CH2:35][CH2:36][CH2:37][CH:32]([S:29]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)(=[O:31])=[O:30])[CH2:33]1)=[O:12])[CH3:3]

参加物

4

反応物 3

HCID 84591,2-Ethanediamine, N1,N1-bis(1-methylethyl)-HCID 682631,1'-CarbonyldiimidazoleHCID 136079833-(Phenylsulfonyl)piperidine

生成物 1

HCID 13608029N-[2-[bis(1-Methylethyl)amino]ethyl]-3-(phenylsulfonyl)-1-piperidinecarboxamide収率 59.8%

実験手順

Following the procedure of Example 16, diisopropylaminoethylamine and 1,1'-carbonyldiimidazole and 3-(phenylsulfonyl)piperidine were reacted to give the title compound which was crystallized from diethyl ether-hexane as white solid in 59.8% yield, m.p. 82.5°-84° C.

後処理

  1. customwere reacted

出典と根拠

ORDレコード
ord-c6a1da51d6b645619f3932338d5acfbd
出典データセット
uspto-grants-1987_02
特許番号
US04642348

関連ノート

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