Hydrogen Bromide → HCID 20058556、化合物

HRID 236545ノート

反応式

HRID 236545 の反応式
Cl.Cl.C[O:4][C:5]1[CH:6]=[C:7]([CH2:13][CH2:14][NH:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][NH:22][CH2:23][CH2:24][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[CH:8]=[CH:9][C:10]=1[O:11]C.[BrH:31]>>[BrH:31].[BrH:31].[C:25]1([CH2:24][CH2:23][NH:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][NH:15][CH2:14][CH2:13][C:7]2[CH:6]=[C:5]([OH:4])[C:10]([OH:11])=[CH:9][CH:8]=2)[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1

参加物

3

反応物 2

HCID 260Hydrogen BromideHCID 20058526N-(2-(3,4-dimethoxyphenyl)ethyl)-N'-(2-phenyl-ethyl)hexan-1,6-diamin Dihydrochlorid

生成物 1

HCID 20058556HCID 20058556、化合物

実験手順

A solution of the diamine product of step (b) (4.75 g) in 48% aqueous hydrobromic acid (70 ml) was heated under reflux in an atmosphere of nitrogen for 3.5 hours. The solid which formed on cooling was filtered off and crystallised from ethanol, to give the title compound as the dihydrobromide salt, (3.1 g), mp 227°-228°.

後処理

  1. temperatureunder reflux in an atmosphere of nitrogen for 3.5 hours
  2. customThe solid which formed
  3. temperatureon cooling
  4. filtrationwas filtered off
  5. customcrystallised from ethanol

出典と根拠

ORDレコード
ord-55ee93655cc54033b12d34a52a9abb1c
出典データセット
uspto-grants-1987_02
特許番号
US04645768

反応ノート

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