Dimethyl Sulfoxide → Benzenamine, 3-[3-(trimethoxysilyl)propoxy]-

Using the general procedure described in the preceding Example 1, a reactor was charged with 300 g (2.75 mole) m-aminophenol, 560 cc dimethylsulfoxide, 600 cc toluene and 216 cc of a 50% aqueous solution of sodium hydroxide (2.70 moles NaOH). The water present in the reactor was removed by azeotropic distillation under a nitrogen atmosphere at a temperature of 120° C. The temperature of the reaction mixture was then lowered to 90° C. and maintained at about this value during the gradual addition of 545 g (2.75 mole) of 3-chloropropyl trimethoxysilane. Following completion of the addition, which required 2 hours, the reaction mixture was heated at the boiling point for 16 hours. The product was recovered and fractionally distilled as described in the preceding example. The fraction boiling from 178° to 180° C. at a pressure of 3 mm of mercury was collected and weighed 630 g (85% yield). The infrared and nuclear magnetic resonance spectra of the distillate confirm the proposed structure ##STR16## A vapor phase chromatogram of the product indicated a purity of greater than 98%.

1. customThe water present in the reactor was removed by azeotropic distillation under a nitrogen atmosphere at a temperature of 120° C
2. customwas then lowered to 90° C.
3. additioncompletion of the addition, which required 2 hours
4. temperaturethe reaction mixture was heated at the boiling point for 16 hours
5. customThe product was recovered
6. distillationfractionally distilled
7. customboiling from 178° to 180° C. at a pressure of 3 mm of mercury
8. customwas collected

ORDレコード

ord-f63076b294ff472d9246588a8564278b

出典データセット

uspto-grants-1987_02

DOI

10.6084/m9.figshare.5104873.v1

特許番号

US04645844