Hydrochloric Acid → HCID 67227007、化合物
反応式
[ClH:1].[CH3:2][O:3][C:4]1[CH:5]=[C:6](/[CH:12]=[C:13](/[C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=2)\[C:14]#[N:15])[CH:7]=[CH:8][C:9]=1[O:10][CH3:11]>C(#N)C>[ClH:1].[CH3:2][O:3][C:4]1[CH:5]=[C:6](/[CH:12]=[C:13](/[C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=2)\[C:14]#[N:15])[CH:7]=[CH:8][C:9]=1[O:10][CH3:11]参加物
4
実験手順
0.1N Hydrochloric acid (4.1 mL) was added to Compound 45 (100 mg), and acetonitrile (20 mL) was added to the mixture, to thereby dissolve the mixture. The solution was stirred in the dark at room temperature for 1 hour, and the solvent was evaporated to dryness. The precipitated crystals were thoroughly dried, to thereby yield the target product (yield: 112 mg, 99%).
後処理
- additionwas added to the mixture
- dissolutionto thereby dissolve the mixture
- customthe solvent was evaporated to dryness
- customThe precipitated crystals were thoroughly dried
出典と根拠
- ORDレコード
- ord-cd53d870db90480488f4595ac76ee0da
- 出典データセット
- uspto-grants-2014_04
- 特許番号
- US08697742B2
反応ノート
読み込み中…