HCID 57517484、化合物 → 1344684-60-1

HRID 2368081ノート

反応式

HRID 2368081 の反応式
[N:1]([CH:4]([CH3:20])[CH2:5][CH2:6][CH:7]1[CH2:12][CH2:11][N:10]([C:13]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14])[CH2:9][CH2:8]1)=[N+]=[N-]>CO.[Pd]>[NH2:1][CH:4]([CH3:20])[CH2:5][CH2:6][CH:7]1[CH2:12][CH2:11][N:10]([C:13]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14])[CH2:9][CH2:8]1

参加物

4

反応物 1

HCID 57517484HCID 57517484、化合物

生成物 1

HCID 575174851344684-60-1収率 103.8%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

A suspension of tert-butyl 4-(3-azidobutyl)piperidine-1-carboxylate (3.81 g) and 5% palladium/carbon (containing water (50%), 800 mg) in methanol (100 mL) was stirred at room temperature for 15 hr under a hydrogen atmosphere. The reaction mixture was filtered, and the filtrate was concentrated under reduced pressure to give the title compound (3.59 g).

後処理

  1. filtrationThe reaction mixture was filtered
  2. concentrationthe filtrate was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-a789f81dd182482882a7121e7fcd1e46
出典データセット
uspto-grants-2014_04
特許番号
US08703758B2

反応ノート

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