Sodium borohydride → HCID 12536095、化合物

HRID 236892ノート

反応式

HRID 236892 の反応式
[O:1]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[C:4](=[O:11])[CH:3]=[C:2]1[CH:12]=[O:13].[BH4-].[Na+]>CO>[OH:13][CH2:12][C:2]1[O:1][C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[C:4](=[O:11])[CH:3]=1

参加物

4

反応物 2

HCID 4311764Sodium borohydrideHCID 104196624-oxo-4H-chromene-2-carbaldehyde

生成物 1

HCID 12536095HCID 12536095、化合物収率 55%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

A mixture of 4H-1-benzopyran-4-one-2-carboxaldehyde (400 mg, 0.0023 m) and sodium borohydride (8.8 mg. 0.0023 m) in methanol (20 ml) was stirred at room temperature for 30 minutes. The solvent was removed at reduced pressure to give a white solid. The solid was washed with water, sucked dry, and recrystallized from ethanol to give white crystals (220 mg, 55%), m.p. 165°-167°.

後処理

  1. customThe solvent was removed at reduced pressure
  2. customto give a white solid
  3. washThe solid was washed with water
  4. customsucked dry
  5. customrecrystallized from ethanol

出典と根拠

ORDレコード
ord-8d43d417ab5b4b19b0f78661905787b3
出典データセット
uspto-grants-1979_06
特許番号
US04158663

反応ノート

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