Thionyl Chloride → HCID 556978、化合物

HRID 2371434ノート

反応式

HRID 2371434 の反応式
[CH:1]1([CH3:15])[CH2:6][CH2:5][CH:4]([CH:7]([CH3:9])[CH3:8])[CH:3]([O:10][CH2:11][C:12](O)=[O:13])[CH2:2]1.S(Cl)([Cl:18])=O>>[CH:1]1([CH3:15])[CH2:6][CH2:5][CH:4]([CH:7]([CH3:9])[CH3:8])[CH:3]([O:10][CH2:11][C:12]([Cl:18])=[O:13])[CH2:2]1

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 978142-((5-Methyl-2-(1-methylethyl)cyclohexyl)oxy)acetic acid

生成物 1

HCID 556978HCID 556978、化合物収率 107.4%

実験手順

0.771 g (3.6 mmol) of (-)-menthoxyacetic acid is stirred under reflux with 2.1 g of thionyl chloride for 4 to 5 h. The thionyl chloride is first removed from the solution by distillation under reduced pressure. 3 ml of dry benzene are then added in order to remove residual thionyl chloride by means of vacuum distillation. 0.9 g of the title compound is obtained.

後処理

  1. customThe thionyl chloride is first removed from the solution by distillation under reduced pressure
  2. addition3 ml of dry benzene are then added in order
  3. customto remove residual thionyl chloride
  4. distillationby means of vacuum distillation

出典と根拠

ORDレコード
ord-e451021af54e4d49b89adeba7e1e916b
出典データセット
uspto-grants-1992_03
特許番号
US05093350

反応ノート

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