Methyl iodide → Ammonium, trimethyl(4-phenylbutyl)-, iodide
反応式
[CH3:1][N:2]([CH2:4][CH2:5][CH2:6][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[CH3:3].[CH3:14][I:15]>CO>[I-:15].[CH3:1][N+:2]([CH2:4][CH2:5][CH2:6][CH2:7][C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1)([CH3:14])[CH3:3]参加物
4
実験手順
To a solution of 287 mg of N,N-dimethyl-4-phenylbutylamine in 3 ml of absolute methanol, 505 μl of methyl iodide was added at a room temperature with stirring, and the mixture was stirred at a room temperature for 6.5 hours. The reaction mixture was concentrated under a reduced pressure, and after adding ethyl acetate allowed to stand for formation of crystal. The crystal was filtered, washed with ethyl acetate, and dried under a reduced pressure to obtain 439 mg of the title compound as a colorless crystal.
後処理
- stirringthe mixture was stirred at a room temperature for 6.5 hours
- concentrationThe reaction mixture was concentrated under a reduced pressure
- additionafter adding ethyl acetate
- filtrationThe crystal was filtered
- washwashed with ethyl acetate
- customdried under a reduced pressure
出典と根拠
- ORDレコード
- ord-964d41e7070c4735a4c768d94607c276
- 出典データセット
- uspto-grants-1992_03
- 特許番号
- US05093370
反応ノート
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