Phosphorus sulfide (P2S5) → HCID 19903350、化合物

HRID 2372374ノート

反応式

HRID 2372374 の反応式
[CH3:1][CH:2]1[CH2:6][NH:5][C:4](=O)[CH:3]1[C:8]([O:10][CH2:11][CH3:12])=[O:9].P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=[S:14]>C1C=CC=CC=1>[CH3:1][CH:2]1[CH2:6][NH:5][C:4](=[S:14])[CH:3]1[C:8]([O:10][CH2:11][CH3:12])=[O:9]

参加物

4

反応物 2

HCID 14817Phosphorus sulfide (P2S5)HCID 19903390HCID 19903390、化合物

生成物 1

HCID 19903350HCID 19903350、化合物収率 146.6%

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

反応条件

温度
50 °C

実験手順

2.5 g of ethyl 4-methyl-2-oxopyrrolidine-3-carboxylate and 3.4 g of phosphorus pentasulfide were added to 50 ml of benzene and stirred at 50° C. for 1 hour. After cooling, the insoluble matters were filtered off and the filtrate was concentrated. The residue was purified by silica gel chromatography to thereby give 2.1 g of the title compound as an oily product.

後処理

  1. temperatureAfter cooling
  2. filtrationthe insoluble matters were filtered off
  3. concentrationthe filtrate was concentrated
  4. customThe residue was purified by silica gel chromatography

出典と根拠

ORDレコード
ord-ecc0947e65be4fd4b37b52f5debd7034
出典データセット
uspto-grants-1992_03
特許番号
US05098919

反応ノート

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