1-Bromopentane → 2-Phenylheptanenitrile

HRID 2372543ノート

反応式

HRID 2372543 の反応式
[OH-].[Na+].Br[CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[CH2:9]([C:16]#[N:17])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[C:16]([CH:9]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[CH2:4][CH2:5][CH2:6][CH2:7][CH3:8])#[N:17]

参加物

4

反応物 3

HCID 80571-BromopentaneHCID 8794PhenylacetonitrileHCID 14798Sodium Hydroxide

生成物 1

HCID 126520202-Phenylheptanenitrile収率 82%

実験手順

Hexadecyltributyl phosphonium hectorite (0.050 mmol) was mixed with 2.0 ml of 50 wt % of aqueous sodium hydroxide, 1-bromopentane (5.0 mmol) and benzyl cyanide 95.0 mmol). After reaction at 50° C. for 2 hr, the emulsion was broken by centrifugation and 1-cyano-1-phenyl hexane was obtained in 82.0% yield.

後処理

  1. customAfter reaction at 50° C. for 2 hr

出典と根拠

ORDレコード
ord-490018294ff544b386804e61fcd9ff78
出典データセット
uspto-grants-1992_03
特許番号
US05099054

反応ノート

読み込み中…