Sodium Chloride → HCID 178446842、化合物

HRID 2372836

反応式

HRID 2372836 の反応式
Cl.[C:2](=[NH:9])(OC)[CH2:3][CH2:4][CH2:5][CH3:6].[NH2:10][CH2:11][C:12]1[CH:17]=[CH:16][C:15]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=2[C:24]#[N:25])=[CH:14][CH:13]=1.C[O-].[Na+].[Cl-].[Na+]>CO>[C:24]([C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=1[C:15]1[CH:14]=[CH:13][C:12]([CH2:11][NH:10][C:2](=[NH:9])[CH2:3][CH2:4][CH2:5][CH3:6])=[CH:17][CH:16]=1)#[N:25]

参加物

6

反応物 4

HCID 5234Sodium ChlorideHCID 13933412-[4-(Aminomethyl)phenyl]benzonitrileHCID 5743465Methyl valerimidate hydrochlorideHCID 10942334Sodium Methoxide

生成物 1

HCID 178446842HCID 178446842、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

The title compound is prepared by stirring one equivalent of methyl valerimidate hydrochloride, one equivalent of 4-aminomethyl-2'-cyanobiphenyl, and one equivalent of sodium methoxide in methanol. The reaction mixture may then be stripped of solvent and the amidine and residual sodium chloride is used directly in the next reaction.

出典と根拠

ORDレコード
ord-5a45ac59856143d1af6da106ced1c6e8
出典データセット
uspto-grants-1992_03
特許番号
US05100897

関連ノート

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