3-Cyanophenol → O-3-cyanophenyl dimethylthiocarbamate

反応式

[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[C:5]#[N:6].[CH3:10][N:11]([CH3:15])[C:12](Cl)=[S:13].[OH-].[K+]>>[CH3:10][N:11]([CH3:15])[C:12](=[S:13])[O:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:4]([C:5]#[N:6])[CH:3]=1

参加物

反応物 3

HCID 133943-Cyanophenol

HCID 14797Potassium Hydroxide

HCID 27871Dimethylthiocarbamoyl chloride

生成物 1

HCID 14795402O-3-cyanophenyl dimethylthiocarbamate

実験手順

If the procedure described in Preparation XI is followed starting from 15 g (126.10-3 mol) of 3-hydroxybenzonitrile, 17.9 g (145.10-3 mol) of dimethylthiocarbamoyl chloride and 7.4 g (132.10-3 mol) of potassium hydroxide, 29 g (quantitative yield) of the expected product are obtained.

出典と根拠

ORDレコード: ord-87ff7015c4e34deb8be2f93ca8168df5
出典データセット: uspto-grants-1992_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05101048

反応ノート

読み込み中…