反応式
Br.Br[C:3]1[CH:8]=[CH:7][N:6]=[N:5][CH:4]=1.[CH3:9][C:10]1[CH:16]=[C:15](B2OC(C)(C)C(C)(C)O2)[CH:14]=[C:13]([CH3:26])[C:11]=1[NH2:12]>>[CH3:9][C:10]1[CH:16]=[C:15]([C:3]2[CH:8]=[CH:7][N:6]=[N:5][CH:4]=2)[CH:14]=[C:13]([CH3:26])[C:11]=1[NH2:12]参加物
3
反応条件
- 温度
- 70 °C
実験手順
The title compound is prepared from 4-bromopyridazine hydrobromide and 2,6-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline following a procedure analogous to that described in Step 2 of Intermediate 62. The mixture is stirred for 12 hours at 70° C. LC (method 9): tR=0.66 min; Mass spectrum (ESI+): m/z=200 [M+H]+.
出典と根拠
- ORDレコード
- ord-7d7e54162d134245a1342a2d2b21f54c
- 出典データセット
- uspto-grants-2014_02
- 特許番号
- US08642585B2
関連ノート
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