1-Benzyloxy-4-(3,3-dimethyl-cyclohex-1-enyl)-benzene → 4-(3,3-Dimethyl-cyclohexyl)-phenol
反応式
C([O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]2[CH2:20][CH2:19][CH2:18][C:17]([CH3:22])([CH3:21])[CH:16]=2)=[CH:11][CH:10]=1)C1C=CC=CC=1>CO.CCOC(C)=O.[Pd]>[CH3:21][C:17]1([CH3:22])[CH2:18][CH2:19][CH2:20][CH:15]([C:12]2[CH:11]=[CH:10][C:9]([OH:8])=[CH:14][CH:13]=2)[CH2:16]1参加物
5
実験手順
To 1-benzyloxy-4-(3,3-dimethyl-cyclohex-1-enyl)-benzene (4.3 g, 16.4 mmol) in MeOH (50 mL) and EtOAc (50 mL) was added 10% Pd/C (0.67 g) under N2. This mixture was stirred under H2 (1 atm) overnight. The reaction mixture was filtered through celite. The filtrate was concentrated to give the title compound as a white solid (3.43 g).
後処理
- filtrationThe reaction mixture was filtered through celite
- concentrationThe filtrate was concentrated
出典と根拠
- ORDレコード
- ord-7dfa238d8d274833ae53a7002e2ed873
- 出典データセット
- uspto-grants-2014_02
- 特許番号
- US08642603B2
反応ノート
読み込み中…