1-(Trifluoromethylcarbonylaminosulphonyl)-3-nitrobenzene → 1-(Trifiuoromethyl carbonylaminosulphonyl)-3-aminobenzene
反応式
[F:1][C:2]([F:19])([F:18])[C:3]([NH:5][S:6]([C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([N+:15]([O-])=O)[CH:10]=1)(=[O:8])=[O:7])=[O:4]>[Pd].O.C(O)C>[F:19][C:2]([F:1])([F:18])[C:3]([NH:5][S:6]([C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([NH2:15])[CH:10]=1)(=[O:7])=[O:8])=[O:4]参加物
5
実験手順
In the same way as that described in Example 11, Step 2, using 1-(trifluoromethylcarbonylaminosulphonyl)-3-nitrobenzene (2.7 g, 9.1 mmol), 10% palladium on carbon (0.25 g, 9% (w/w)) in water (3 ml) and ethanol (70 ml), the title compound (1.7 g, 70%) was afforded as a colourless solid. mp 106°-108° C. 1H NMR (360 MHz, D6 -DMSO) δ 6.59 (1H, m), 6.88 (1H, m), 7.02 (2H, m).
出典と根拠
- ORDレコード
- ord-3c6bb15660594b0b8bc84f15131448e1
- 出典データセット
- uspto-grants-1994_11
- 特許番号
- US05360802
反応ノート
読み込み中…