Potassium Carbonate → p-Methoxybenzamidoxime

HRID 2379720

反応式

HRID 2379720 の反応式
[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:6]([C:7]#[N:8])=[CH:5][CH:4]=1.Cl.[NH2:12][OH:13].C(=O)([O-])[O-].[K+].[K+]>C(O)C>[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:6]([C:7](=[N:12][OH:13])[NH2:8])=[CH:5][CH:4]=1

参加物

5

反応物 3

HCID 11430Potassium CarbonateHCID 701294-MethoxybenzonitrileHCID 443297Hydroxyamine hydrochloride

生成物 1

HCID 21471p-Methoxybenzamidoxime収率 20%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

13.32 g (0.1 mol) 4-methoxybenzonitrile, 20.85 g (0.3 mol) of hydroxylamine hydrochloride and 41.40 g (0.3 mol) potassium carbonate was added to 400 mL absolute ethanol and refluxed 21 hours. The product was filtered and recrystallized from methanol to give 3.12 g (0.02 mol) of 4-methoxybenzamide oxime.

後処理

  1. temperaturerefluxed 21 hours
  2. filtrationThe product was filtered
  3. customrecrystallized from methanol

出典と根拠

ORDレコード
ord-147606ac386542db85baec4e3378b6cd
出典データセット
uspto-grants-1994_11
特許番号
US05364865

関連ノート

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