Formaldehyde → HCID 178430444、化合物
反応式
C([N:20]1[CH:24]=[C:23]([CH:25]([CH3:28])[CH2:26][NH2:27])[N:22]=[CH:21]1)(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1.[CH2:29]=O>Cl>[CH3:28][CH:25]1[CH2:26][NH:27][CH2:29][CH:24]2[N:20]=[CH:21][NH:22][CH:23]12参加物
4
反応条件
- 温度
- 95 °C
実験手順
3.2 g 2-(1-trityl-1H-imidazol-4-yl)-propylamine is suspended in aqueous HCl (1 N). After the addition of 2.9 mL formaldehyde the mixture is heated to 95° C. with stirring. After 5 h it is cooled to RT, suction filtered to remove the precipitate formed and the solvent is eliminated in vacuo. This crude product is used in the following reaction step without further purification.
後処理
- temperatureAfter 5 h it is cooled to RT
- filtrationsuction filtered
- customto remove the precipitate
- customformed
出典と根拠
- ORDレコード
- ord-e73142bd30874a93aca363f3d2483565
- 出典データセット
- uspto-grants-2012_09
- 特許番号
- US08258129B2
反応ノート
読み込み中…