Hydrochloric Acid → HCID 178441102、化合物

反応式

C([O:5][PH:6]([CH2:8][C:9]1[CH:14]=[C:13]([C:15]([CH3:18])([CH3:17])[CH3:16])[C:12]([OH:19])=[C:11]([C:20]([CH3:23])([CH3:22])[CH3:21])[CH:10]=1)=[O:7])CCC.Cl>[OH-].[Na+].C(O)(C)C>[C:15]([C:13]1[CH:14]=[C:9]([CH:10]=[C:11]([C:20]([CH3:23])([CH3:22])[CH3:21])[C:12]=1[OH:19])[CH2:8][PH:6](=[O:5])[OH:7])([CH3:18])([CH3:17])[CH3:16]

参加物

反応条件

温度: 100 °C

実験手順

17 grams (50 mmol) of (3,5-di-tert-butyl-4-hydroxy-benzyl)-phosphinic acid butyl ester in a mixture of 100 mL of 2.5 N sodium hydroxide solution and 10 mL of isopropanol is heated at 100° C. for 1 hour. The cooled reaction mixture is poured into a mixture of 25 mL of concentrated hydrochloric acid and 200 mL of ice. The product is extracted into 400 mL of chloroform and the chloroform layer is washed with 200 mL of water and then dried over sodium sulfate.