Isopropylamine → [3-(2-Chloro-pyrimidin-4-yl)-benzyl]-isopropyl-amine
反応式
C(OC(=O)NC[CH2:9][CH2:10][NH:11][CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([C:19]2[CH:24]=[CH:23][N:22]=[C:21]([Cl:25])[N:20]=2)[CH:14]=1)(C)(C)C.[CH:27](N)(C)C>>[Cl:25][C:21]1[N:20]=[C:19]([C:15]2[CH:14]=[C:13]([CH:18]=[CH:17][CH:16]=2)[CH2:12][NH:11][CH:10]([CH3:9])[CH3:27])[CH:24]=[CH:23][N:22]=1参加物
3
実験手順
Intermediate 2 was coupled with isopropylamine following procedure B. LC-MS showed the product had the expected M+H+ of 262.
出典と根拠
- ORDレコード
- ord-41d9765b78d44e43ada9bf1efa2a43c3
- 出典データセット
- uspto-grants-2012_09
- 特許番号
- US08268822B2
反応ノート
読み込み中…