Hydrogen Sulfide → 4-Pyridineethanethioamide
反応式
[SH2:1].[N:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]#[N:10])=[CH:4][CH:3]=1>CO>[N:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9](=[S:1])[NH2:10])=[CH:4][CH:3]=1参加物
4
反応条件
- 温度
- 25 °C
実験手順
Hydrogen sulfide was passed through a solution of 2-(pyridin-4-yl)acetonitrile (2.5 g) in 30% strength ammoniacal methanol (12 ml) at 0° C. for 30 minutes. The resulting reaction mixture was stirred at 25° C. for 16 hours. The solid which had precipitated was filtered out, washed with ether and dried. The desired product was obtained in a yield of 76%.
後処理
- customThe resulting reaction mixture
- customThe solid which had precipitated
- filtrationwas filtered out
- washwashed with ether
- customdried
出典と根拠
- ORDレコード
- ord-eded4053db374855904b29a20391c05a
- 出典データセット
- uspto-grants-2012_09
- 特許番号
- US08268814B2
反応ノート
読み込み中…