Isopropylamine → N-Isopropyl-2-Nitro-4-(Trifluoromethyl)Aniline
反応式
F[C:2]1[CH:7]=[CH:6][C:5]([C:8]([F:11])([F:10])[F:9])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].CN1CCCC1=O.[CH:22]([NH2:25])([CH3:24])[CH3:23]>O>[CH:22]([NH:25][C:2]1[CH:7]=[CH:6][C:5]([C:8]([F:11])([F:10])[F:9])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13])([CH3:24])[CH3:23]参加物
5
実験手順
To a mixture of 5.23 g of 4-fluoro-3-nitro-benzo trifluoride and 25 ml of N-methylpyrrolidone was added 3.69 g of isopropylamine under ice cool, and the mixture was stirred for 1 hour at room temperature. The reaction mixture was poured into water, the deposited solid was collected by filtration. This solid was washed with water, then, dried under reduced pressure to obtain 5.90 g of N-isopropyl-2-nitro-4-trifluoromethylaniline.
後処理
- temperaturecool
- filtrationthe deposited solid was collected by filtration
- washThis solid was washed with water
- customdried under reduced pressure
出典と根拠
- ORDレコード
- ord-aa1aefe9f5c24987b10701e01905be78
- 出典データセット
- uspto-grants-2012_09
- 特許番号
- US08273764B2
反応ノート
読み込み中…