1-(3-Methyl-4-nitrophenyl)-1,2,4-triazole → 2-Methyl-4-[1,2,4]triazol-1-yl-phenylamine
反応式
[CH3:1][C:2]1[CH:3]=[C:4]([N:11]2[CH:15]=[N:14][CH:13]=[N:12]2)[CH:5]=[CH:6][C:7]=1[N+:8]([O-])=O>C(O)C.[Pd]>[N:11]1([C:4]2[CH:5]=[CH:6][C:7]([NH2:8])=[C:2]([CH3:1])[CH:3]=2)[CH:15]=[N:14][CH:13]=[N:12]1参加物
4
実験手順
A mixture of 1-(3-methyl-4-nitrophenyl)-1,2,4-triazole (D61, 1.0 g), 10% Pd/C (200 mg) in ethanol (50 ml) was hydrogenated at ambient temperature and pressure for 5 hours. The reaction mixture was filtered through kieselguhr and the filtrate evaporated to leave the title compound (0.85 g, 98%) which was used directly in the next stage.
後処理
- customwas hydrogenated at ambient temperature
- filtrationThe reaction mixture was filtered through kieselguhr
- customthe filtrate evaporated
出典と根拠
- ORDレコード
- ord-2e8970bf19a04719be032a263866d768
- 出典データセット
- uspto-grants-1998_09
- 特許番号
- US05801170
反応ノート
読み込み中…