Formic Acid → 2'-Methoxy-5'-nitroformanilide
反応式
[CH:1]([OH:3])=O.C(OC(=O)C)(=O)C.[CH3:11][O:12][C:13]1[CH:19]=[CH:18][C:17]([N+:20]([O-:22])=[O:21])=[CH:16][C:14]=1[NH2:15]>C1COCC1>[CH3:11][O:12][C:13]1[CH:19]=[CH:18][C:17]([N+:20]([O-:22])=[O:21])=[CH:16][C:14]=1[NH:15][CH:1]=[O:3]参加物
5
反応条件
- 温度
- 55 °C
実験手順
A mixture of formic acid (0.45 ml, 0.012 mole) and acetic anhydride (1.06 ml, 0.011 mole) was stirred at 55° C. under Ar for 2 h, and cooled to room temperature. Dry THF (10 ml) was added. To this solution was added 2-methoxy-5-nitroaniline (0.69 g, 0.004 mole). After stirring for 1 h, the suspension was evaporated in vacuo to leave the title compound as a brown solid (0.80 g, 99%).
後処理
- temperaturecooled to room temperature
- stirringAfter stirring for 1 h
- customthe suspension was evaporated in vacuo
出典と根拠
- ORDレコード
- ord-7c7e3a1ae1ef4d34921aa31fbc44a50f
- 出典データセット
- uspto-grants-1998_09
- 特許番号
- US05801170
反応ノート
読み込み中…