Acrylamide → HCID 18975619、化合物

HRID 2393340ノート

反応式

HRID 2393340 の反応式
Cl.[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([Cl:9])=[CH:5][C:4]=1[NH:10][NH2:11].[C:12](N)(=[O:15])[CH:13]=[CH2:14].[Na]>C(O)C.C1(C)C=CC=CC=1>[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([Cl:9])=[CH:5][C:4]=1[N:10]1[CH2:14][CH2:13][C:12](=[O:15])[NH:11]1

参加物

6

反応物 3

HCID 6579AcrylamideHCID 3084937(2,5-Dichlorophenyl)hydrazine monohydrochlorideHCID 5360545Sodium

生成物 1

HCID 18975619HCID 18975619、化合物

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒HCID 1140Toluene溶媒

実験手順

2,5-Dichlorophenylhydrazine hydrochloride (240 g, 1.1 mol) and acrylamide (100 g, 1.4 mol) is refluxed in a solution of sodium (56 g, 2.4 mol) in ethanol (1000 ml) and toluene (1000 ml) for 3 hours. Evaporation of the solvents, acidification with acetic acid dilution with water, filtration and drying (high vacuum, +100° C.) gives the 1-(2,5-dichlorophenyl)-3-pyrazolidone.

後処理

  1. customEvaporation of the solvents, acidification with acetic acid dilution
  2. filtrationwith water, filtration
  3. customdrying (high vacuum, +100° C.)

出典と根拠

ORDレコード
ord-f720fd69f2e04dce9921140d2ca36ee8
出典データセット
uspto-grants-1998_09
特許番号
US05807863

反応ノート

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