Acetonitrile → HCID 15292877、化合物

反応式

[NH2:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([NH:8][NH2:9])=[O:7])=[CH:4][CH:3]=1.[CH2:12]([S:14]N=C=O)C.[C:18](#[N:20])[CH3:19]>>[NH2:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([NH:8][NH:9][C:12]([NH:20][CH2:18][CH3:19])=[S:14])=[O:7])=[CH:4][CH:3]=1

参加物

反応物 3

HCID 6342Acetonitrile

HCID 214504-Aminobenzoic acid hydrazide

HCID 21933416HCID 21933416、化合物

生成物 1

HCID 15292877HCID 15292877、化合物

反応条件

温度: 24 °C

実験手順

A mixture of 4.5 g (29.8 mmol) of 4-aminobenzoic acid hydrazide and 2.6 mL of ethylthioisocyanate in 15 mL of acetonitrile was heated at reflux for 3 hours. The solution was cooled to 24° C., and the precipitate was collected by filtration and dried under vacuum to afford 7.0 g of 1-(4-aminobenzoyl)-4-ethylthiosemicarbazide, mp 113°-115° C.