Acetic Anhydride → (E,E)-1-acetoxy-4-ethyl-2,4-heptadiene
反応式
[CH2:1](/[C:3](=[CH:8]\[CH2:9][CH3:10])/[CH:4]=[CH:5]/[CH2:6][OH:7])[CH3:2].[C:11](OC(=O)C)(=[O:13])[CH3:12]>N1C=CC=CC=1>[C:11]([O:7][CH2:6]/[CH:5]=[CH:4]/[C:3](/[CH2:1][CH3:2])=[CH:8]/[CH2:9][CH3:10])(=[O:13])[CH3:12]参加物
4
実験手順
To a solution of (E,E)-4-ethyl-2,4-heptadien-1-ol (10.1 g) in pyridine (29 g) at 0° C. was added dropwise acetic anhydride (22.2 g). After two hours at room temperature, the reaction mixture was evaporated in vacuo. The residue was diluted with ethyl acetate, washed with 0.5N hydrochloric acid and brine, dried over anhydrous magnesium sulfate, and evaporated in vacuo. The residue was chromatographed on silica gel (5% ethyl acetate in hexane) to give (E,E)-1-acetoxy-4-ethyl-2,4-heptadiene (9.75 g) as an oil.
後処理
- customthe reaction mixture was evaporated in vacuo
- additionThe residue was diluted with ethyl acetate
- washwashed with 0.5N hydrochloric acid and brine
- dry with materialdried over anhydrous magnesium sulfate
- customevaporated in vacuo
- customThe residue was chromatographed on silica gel (5% ethyl acetate in hexane)
出典と根拠
- ORDレコード
- ord-4533bf6cd86448a4b3bb372bb1d98a34
- 出典データセット
- uspto-grants-1996_02
- 特許番号
- US05495023
反応ノート
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