Potassium Hydroxide → HCID 21437243、化合物
反応式
[OH-].[K+].Cl.[CH:4]1([CH2:7][NH2:8])[CH2:6][CH2:5]1.[CH2:9]([S:11][C:12]1[C:17]2[C:18]([C:28]3[CH:33]=[CH:32][CH:31]=[C:30]([Cl:34])[CH:29]=3)=[N:19][CH2:20][C:21]3[N:22]([C:23]([CH2:26]Cl)=[N:24][N:25]=3)[C:16]=2[CH:15]=[CH:14][CH:13]=1)[CH3:10]>O1CCCC1>[CH2:9]([S:11][C:12]1[C:17]2[C:18]([C:28]3[CH:33]=[CH:32][CH:31]=[C:30]([Cl:34])[CH:29]=3)=[N:19][CH2:20][C:21]3[N:22]([C:23]([CH2:26][NH:8][CH2:7][CH:4]4[CH2:6][CH2:5]4)=[N:24][N:25]=3)[C:16]=2[CH:15]=[CH:14][CH:13]=1)[CH3:10]参加物
5
実験手順
In the manner given in Example 3, a solution of potassium hydroxide and (cyclopropylmethyl)amine hydrochloride is treated with a solution of 7-(ethylthio)-1-(chloromethyl)-6-(m-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine in tetrahydrofuran to give 7-(ethylthio)-1-[[(cyclopropylmethyl)amino]methyl]-6-(m-chlorophenyl)-4H-s-triazolo-[4,3-a][1,4]benzodiazepine.