Hydrochloric Acid → 3.5-Diethyl-4-methoxybenzoic acid

HRID 2398492ノート

反応式

HRID 2398492 の反応式
C[O:2][C:3](=[O:16])[C:4]1[CH:9]=[C:8]([CH2:10][CH3:11])[C:7]([O:12][CH3:13])=[C:6]([CH2:14][CH3:15])[CH:5]=1.[OH-].[Na+].Cl>O>[CH2:10]([C:8]1[CH:9]=[C:4]([CH:5]=[C:6]([CH2:14][CH3:15])[C:7]=1[O:12][CH3:13])[C:3]([OH:16])=[O:2])[CH3:11]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 53900511HCID 53900511、化合物

生成物 1

HCID 234456633.5-Diethyl-4-methoxybenzoic acid

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A mixture of 11.6 g. (0.052 mol.) of 3,5-diethyl-4-methoxybenzoic acid methyl ester and 3.5 g. (0.09 mol.) of sodium hydroxide in 150 ml. of water is refluxed for two hours. The reaction mixture is cooled and acidified with 10% aqueous hydrochloric acid to give 3,5-diethyl-4-methoxybenzoic acid. The acid is refluxed with thionyl chloride as described in the procedure of Example 27 to give 3,5-diethyl-4-methoxybenzoyl chloride.

後処理

  1. additionA mixture of 11.6 g
  2. temperatureThe reaction mixture is cooled

出典と根拠

ORDレコード
ord-b050c31cfced4c079c261a63c82fc88d
出典データセット
uspto-grants-1977_05
特許番号
US04024273

反応ノート

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