N-bromobutanimide → Ethyl 2-Methyl-3-furoate

HRID 2398649

反応式

HRID 2398649 の反応式
[C:1]([C:4](=[CH:10][CH3:11])[C:5]([O:7][CH2:8][CH3:9])=[O:6])(=[O:3])[CH3:2].BrN1C(=O)CCC1=O>C(Cl)(Cl)(Cl)Cl>[CH3:2][C:1]1[O:3][CH:11]=[CH:10][C:4]=1[C:5]([O:7][CH2:8][CH3:9])=[O:6]

参加物

4

反応物 2

HCID 67184N-bromobutanimideHCID 53941670Ethyl 2-acetylbut-2-enoate

生成物 1

HCID 261900Ethyl 2-Methyl-3-furoate収率 24%

試薬・触媒・溶媒 1

HCID 5943Carbon Tetrachloride溶媒

実験手順

A mixture of 3.12 g (0.02 mole) ethyl 2-acetyl-2-butenoate and 3.56 g (0.02 mole) N-bromosuccinimide in 50 ml of carbon tetrachloride was heated at reflux for 19 hours. After cooling, the insoluble succinimide was removed by filtration and the solution concentrated by rotary evaporation. Distillation of the crude product gave 0.73 g (24%) of ethyl 2-methyl-3-furoate, bp 87°-9° C. (20 mm).

後処理

  1. temperaturewas heated
  2. temperatureat reflux for 19 hours
  3. temperatureAfter cooling
  4. customthe insoluble succinimide was removed by filtration
  5. concentrationthe solution concentrated by rotary evaporation
  6. distillationDistillation of the crude product

出典と根拠

ORDレコード
ord-9b92a50ab88542f7ab03d1dc7dab9998
出典データセット
uspto-grants-1977_05
特許番号
US04025537

関連ノート

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