N-bromobutanimide → HCID 12452841、化合物
反応式
[C:1]([C:4](=[CH:10][CH2:11][CH:12]([CH3:14])[CH3:13])[C:5]([O:7][CH2:8][CH3:9])=[O:6])(=[O:3])[CH3:2].BrN1C(=O)CCC1=O>C(Cl)(Cl)(Cl)Cl>[CH:12]([C:11]1[O:3][C:1]([CH3:2])=[C:4]([C:5]([O:7][CH2:8][CH3:9])=[O:6])[CH:10]=1)([CH3:13])[CH3:14]参加物
4
実験手順
A mixture of 3.97 g (0.02 mole) ethyl 2-acetyl-5-methyl-2-hexenoate and 3.55 g (0.02 mole) N-bromosuccinimide in 50 ml of carbon tetrachloride was heated at reflux for 2.5 hours. After cooling, the succinimide was removed by filtration and the solution concentrated by rotary evaporation. Distillation of the crude product gave 3.33 g (85% ) of ethyl 5-isopropyl-2-methyl-3-furoate, bp 112°-114° C. (11 mm).
後処理
- temperaturewas heated
- temperatureat reflux for 2.5 hours
- temperatureAfter cooling
- customthe succinimide was removed by filtration
- concentrationthe solution concentrated by rotary evaporation
- distillationDistillation of the crude product
出典と根拠
- ORDレコード
- ord-0728c37e81da434bb73d2191524a42e2
- 出典データセット
- uspto-grants-1977_05
- 特許番号
- US04025537
反応ノート
読み込み中…