3-Furancarboxylic acid, 5-methyl-2-phenyl-, ethyl ester → 5-Methyl-2-phenylfuran-3-carboxylic acid
反応式
[CH3:1][C:2]1[O:6][C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[C:4]([C:13]([O:15]CC)=[O:14])[CH:3]=1>[OH-].[Na+].C(O)C>[CH3:1][C:2]1[O:6][C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[C:4]([C:13]([OH:15])=[O:14])[CH:3]=1参加物
4
実験手順
Saponification of 0.5 g of the ester was accomplished by refluxing 12 hours in 10 ml of 25% aqueous sodium hydroxide and 5 ml of ethanol. Acidification precipitated the crude acid, which was recrystallized from water-ethanol to give 5-methyl-2-phenyl-3-furoic acid, mp 146°-147.5° C.
後処理
- customAcidification precipitated the crude acid, which
- customwas recrystallized from water-ethanol
出典と根拠
- ORDレコード
- ord-51024104c9c6412fa0774d943abb5260
- 出典データセット
- uspto-grants-1977_05
- 特許番号
- US04025537
反応ノート
読み込み中…