Thiosemicarbazide → 1-(1-Methyl-5-nitro-2-imidazolecarbonyl)-3-thiosemicarbazide
反応式
[CH3:1][N:2]1[C:6]([N+:7]([O-:9])=[O:8])=[CH:5][N:4]=[C:3]1[C:10](Cl)=[O:11].[NH2:13][NH:14][C:15]([NH2:17])=[S:16]>O1CCCC1>[CH3:1][N:2]1[C:6]([N+:7]([O-:9])=[O:8])=[CH:5][N:4]=[C:3]1[C:10]([NH:13][NH:14][C:15]([NH2:17])=[S:16])=[O:11]参加物
4
実験手順
To 1-methyl-5-nitro-2-imidazolecarboxylic acid chloride (1.1 g.) in 25 ml. of dry tetrahydrofuran is added 0.55 g. powdered thiosemicarbazide and the mixture is stirred at room temperature for 24 hours. The reaction mixture is evaporated to dryness and water is added. The solution is made basic with sodium hydroxide and the solid is filtered, washed with water and dried affording 1-(1-methyl-5-nitro-2-imidazolecarbonyl)-3-thiosemicarbazide.
後処理
- customThe reaction mixture is evaporated to dryness and water
- additionis added
- filtrationthe solid is filtered
- washwashed with water
- customdried
出典と根拠
- ORDレコード
- ord-9666a97a95734b01b73d32dae1d697a8
- 出典データセット
- uspto-grants-1977_05
- 特許番号
- US04026903
反応ノート
読み込み中…