Phthalic Anhydride → 1,2-Benzenedicarboxylic acid, 1-(2-((1-oxo-2-propen-1-yl)oxy)ethyl) ester

HRID 240208ノート

反応式

HRID 240208 の反応式
[C:1]1(=[O:11])[O:6][C:4](=[O:5])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.[C:12]([O:16][CH2:17][CH2:18][OH:19])(=[O:15])[CH:13]=[CH2:14]>C(N(CC)CC)C>[C:12]([O:16][CH2:17][CH2:18][O:19][C:4](=[O:5])[C:3]1[C:2](=[CH:10][CH:9]=[CH:8][CH:7]=1)[C:1]([OH:6])=[O:11])(=[O:15])[CH:13]=[CH2:14]

参加物

4

反応物 2

HCID 6811Phthalic AnhydrideHCID 131652-Hydroxyethyl acrylate

生成物 1

HCID 1217431,2-Benzenedicarboxylic acid, 1-(2-((1-oxo-2-propen-1-yl)oxy)ethyl) ester

試薬・触媒・溶媒 1

HCID 8471Triethylamine溶媒

反応条件

温度
75 °C

実験手順

Phthalic anhydride (112.1 grams), 2-hydroxyethyl acrylate (87.9 grams), and triethylamine (0.44 grams) were mixed in a round bottom flask. A small amount of dry air was bubbled into the liquid reaction mixture. The reaction mixture was mixed and heated to 75° C. and held at that temperature for six hours. The product was cooled to room temperature. NMR was used to confirm that the product was phthalic acid mono-(2-acryloyloxy-ethyl)ester. The product partially crystallized over time. The product was mixed with 1-methoxy-2-propanol to obtain a 50 weight percent solution.

後処理

  1. customA small amount of dry air was bubbled into the liquid reaction mixture
  2. additionThe reaction mixture was mixed
  3. temperatureThe product was cooled to room temperature
  4. customThe product partially crystallized over time
  5. additionThe product was mixed with 1-methoxy-2-propanol
  6. customto obtain a 50 weight percent solution

出典と根拠

ORDレコード
ord-3efe79017a454dceab2053fce36d7183
出典データセット
uspto-grants-2014_02
特許番号
US08647510B2

反応ノート

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