Benzalkonium → Benzalkonium trans-Cinnamate

HRID 2403117

反応式

HRID 2403117 の反応式
[CH3:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][N+:14]([CH2:17][C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1)([CH3:16])[CH3:15].[Cl-].[C:25]([OH:35])(=[O:34])/[CH:26]=[CH:27]/[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1.CCCCCCCCCCCCC[N+](CC1C=CC=CC=1)(C)C.C(Cl)(Cl)Cl>CS(C)=O>[CH3:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][N+:14]([CH2:17][C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1)([CH3:16])[CH3:15].[C:25]([O-:35])(=[O:34])/[CH:26]=[CH:27]/[C:28]1[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=1

参加物

6

反応物 4

HCID 2330BenzalkoniumHCID 6212ChloroformHCID 444539Cinnamic AcidHCID 3014024Benzalkonium Chloride

生成物 1

HCID 86612073Benzalkonium trans-Cinnamate収率 90%

試薬・触媒・溶媒 1

HCID 679Dimethyl Sulfoxide溶媒

反応条件

温度
90 °C

実験手順

Benzalkonium chloride (0.001 mol) was dissolved in warm distilled water. trans-Cinnamic acid (0.001 mol) was added to the benzalkonium solution. The reaction solution was stirred at 90° C. for 4 hours. The reaction solution was cooled to room temperature then 60 mL of chloroform was added. The two phases were separated and the chloroform phase was washed several times with cool distilled water to remove any inorganic salt. The presence of chloride anions was monitored by silver nitrate test. A rotary evaporator removed the chloroform and an orange viscous liquid was obtained in 90% yield. 1H and 13C NMR (DMSO) were obtained. Melting point (hot plate apparatus)=liquid at room temperature.

後処理

  1. temperaturein warm
  2. distillationdistilled water
  3. temperatureThe reaction solution was cooled to room temperature
  4. customThe two phases were separated
  5. washthe chloroform phase was washed several times
  6. temperaturewith cool
  7. distillationdistilled water
  8. customto remove any inorganic salt
  9. customA rotary evaporator
  10. customremoved the chloroform
  11. customan orange viscous liquid was obtained in 90% yield
  12. customat room temperature

出典と根拠

ORDレコード
ord-da1817bee8b748d48d7d816f024c4ed6
出典データセット
uspto-grants-2014_08
特許番号
US08802596B2

関連ノート

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