Water → Dibenzyl ether

HRID 2405

反応式

HRID 2405 の反応式
[CH2:1](Cl)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH2:9]>>[CH2:1]([OH:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:1]([O:9][CH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 962WaterHCID 7503Benzyl Chloride

生成物 2

HCID 244Benzyl AlcoholHCID 7657Dibenzyl ether収率 5.4%

実験手順

126.5 g (1 mol) of benzyl chloride and 180 g (10 mol) of water were rapidly heated to reflux in a flask with baffles and propeller stirrer with vigorous stirring (250 rpm) under nitrogen. After 240 min reaction time, the mixture was rapidly cooled, the organic phase was separated off after addition of toluene, and analyzed by gas chromatography. It was found that 48 g of the benzyl chloride had been converted to give a yield of benzyl alcohol of 37 g and about 3.6 g dibenzyl ether, corresponding to a conversion of 38% and a yield of benzyl alcohol of 91%. The hydrochloric acid formed had a concentration of about 7.4%.

後処理

  1. temperatureto reflux in a flask with baffles and propeller stirrer
  2. customAfter 240 min reaction time
  3. temperaturethe mixture was rapidly cooled
  4. customthe organic phase was separated off
  5. additionafter addition of toluene

出典と根拠

ORDレコード
ord-ef5596a4da4243beba3c5680c17f513e
出典データセット
uspto-grants-1998_03
特許番号
US05728897

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