Tert-butyl 4-(benzyloxy)pyridin-2-ylcarbamate → HCID 178452896、化合物
反応式
C([O:8][C:9]1[CH:14]=[CH:13][N:12]=[C:11]([NH:15][C:16](=[O:22])[O:17][C:18]([CH3:21])([CH3:20])[CH3:19])[CH:10]=1)C1C=CC=CC=1>CO.[Pd]>[OH:8][C:9]1[CH:14]=[CH:13][N:12]=[C:11]([NH:15][C:16](=[O:22])[O:17][C:18]([CH3:20])([CH3:19])[CH3:21])[CH:10]=1参加物
4
実験手順
To a solution of tert-butyl 4-(benzyloxy)pyridin-2-ylcarbamate (5.89 g, 19.6 mmol) in methanol was added palladium on carbon (1.04 g, 0.981 mmol). After stirring under a hydrogen balloon at room temperature for 70 minutes, the solids were removed by filtration. The filtrate was concentrated under reduced pressure and solidified under high vacuum to provide the product (4.12 g, 99%) as white solid.
後処理
- customthe solids were removed by filtration
- concentrationThe filtrate was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-f8e0b6e7abb3461aa7b5e1fed25787b0
- 出典データセット
- uspto-grants-2014_02
- 特許番号
- US08648087B2
反応ノート
読み込み中…