関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Piperidine | HCID 8082 | — |
| 反応物 | 1,3,5-Triazine | HCID 9262 | — |
| 反応物 | 5-Hydroxyanthranilic acid | HCID 164592 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | HCID 178515775 | HCID 178515775 | 72.3% |
反応手順
A mixture of 2-amino-5-hydroxybenzoic acid (19.64 g, 128 mmol), 1,3,5-triazine (15.6 g, 192 mmol), and piperidine (9 mL, 92.4 mmol) were heated to 60° C. in methanol (60 mL) for 2 hours. After cooling to 0° C., the mixture was filtered. The solid was washed with cold methanol and dried under high vacuum to provide the product (15 g, 72%) as white solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08648087B2 |
|---|
| 出典データセット | uspto-grants-2014_02 |
|---|
| ORD ID | ord-135b540daf344f7390b3f86a9f694876 |
|---|
| 出典メモ | uspto-grants-2014_02 |
|---|
